• The lack of a single identified correlate of

  2019-05-24

  

  The lack of a single identified correlate of protection for LAIV should not deter future immunogenicity studies in resource-limited settings, especially using systems vaccinology approaches designed to dissect the complex interplay of innate and adaptive pathways following vaccination. John C Victor

• Although the NCCN IPI is a promising simple

  2019-05-23

  

  Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta

• br Prognosis The management of AML in the elderly

  2019-05-23

  

  Prognosis The management of AML in the elderly patient presents a significant challenge for hematologists. Careful evaluation of both patient and disease is required in each individual case to make optimal management decisions, and maximize the benefit to the patient. Apart from the extremely old

• It is noteworthy that even

  2019-05-23

  

  It is noteworthy that, even with low tumor burden in these patients following CR, peak value at CR status is still a useful indicator for OS, both in the whole cohort, and more importantly, in the intermediate-risk subgroup. Slope is mainly determined by tissue vascularization and perfusion, but cap

• br Ablation strategies from targeted to

  2019-05-23

  

  Ablation strategies – from targeted to homogenization The techniques and principles originally developed in postinfarction scar have been translated and applied to patients with various etiologies of fibrosis and confluent scar including Chagasic cardiomyopathy, nonischemic cardiomyopathy, arrhyt

• br Discussion We successfully prevented the initiation of AF

  2019-05-23

  

  Discussion We successfully prevented the initiation of AF without inhibiting the AF-triggering APB, and eliminated the AF-triggering APB located close to the sinus node without damage to sinus node function. Nifekalant is an IKr antagonist that prolongs the duration of myocardial monensin and pr

• br Conclusion Our findings may help physicians in selecting

  2019-05-23

  

  Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic Puromycin is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it m

• A year old female patient was

  2019-05-23

  

  A 55-year-old female patient was referred to us for harpagoside of an implantable cardioverter-defibrillator (ICD) after cardiac arrest due to idiopathic ventricular fibrillation. As she was young and had no indications for cardiac resynchronization therapy or bradycardia support, she was screened

• In a previous report it was speculated that

  2019-05-23

  

  In a previous report, it was speculated that withdrawal syndrome after IM cessation was related to a loss of blocking tyrosine kinases, such as c-kit and platelet-derived growth factor receptor (PDGFR) [2]. The inhibition of c-kit and PDGFR by IM reduces and increases the number of osteoclasts and o

• br After several decades of

  2019-05-23

  

  After several decades of community-based interventions and surveillance, on Nov 15, 2016, Morocco was recognised by WHO as having eliminated trachoma as a public health problem. A formal ceremony, involving the handover of a letter of recognition from Margaret Chan, WHO\'s Director-General, marked

• The Mexico City Policy is also flawed

  2019-05-23

  

  The Mexico City Policy is also flawed on evidentiary and public health grounds. A 2011 study found that enforcement of the Mexico City Policy by the George W Bush administration led to an increase in abortion rates in sub-Saharan Africa, probably because of decreased contraception access and increas

• br Methods We reviewed http www

  2019-05-23

  

  Methods We reviewed http://www.canadiancancertrials.ca/ and http://www.ontario.canadiancancertrials.ca/ in order to identify ongoing bone oncology-related trials. We used the keywords: bone, bone metastasis, bone treatment, cancer therapy induced bone loss and bisphosphonates for searching. We al

• Introduction Lung cancer is the

  2019-05-22

  

  Introduction Lung cancer is the most common and deadly malignancy in Taiwan, the cause of an estimated 33,919 new cases between 2002 and 2008. Although the 5-year survival rate is only 15.9%, the overall survival rate is as high as 60.7% in patients whose tumors are confined to the primary site at

• After the RFCA neither sustained VT

  2019-05-22

  

  After the RFCA, neither sustained VT nor the VPCs that triggered the VT were recorded. The patient was fitted with a WCD (LifeVest, Zoll, Pittsburgh, PA, USA) on the third day post-ablation, and sotalol 80mg a day was started. He was discharged from the coronary care unit the following day. During c

• Bile acids are cholesterol derivatives produced only in the

  2019-05-22

  

  Bile acids are cholesterol derivatives produced only in the hepatocytes of the liver. Hepatic bile acid synthesis represents the only quantitatively significant route for cholesterol elimination. Bile acids are amphipathic physiological detergents that facilitate dietary cholesterol, lipid and fat-s

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