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Erlotinib receptor br Effects of BCAAs on
2024-11-11

Effects of BCAAs on glucose metabolism Insulin plays an exclusive role in regulation of glucose metabolism, and obesity and type 2 diabetes induce hyperinsulinemia due to insulin resistance. Plasma BCAA concentrations are increased by 14–20% in patients with hyperinsulinemia under overnight fasti
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On the other hand it is important to note
2024-11-11

On the other hand, it is important to note that FR is different from the regulation of daily/circadian rhythms [44]. Based on models of physical systems [45], [46], it has been hypothesized that fractal physiological fluctuations reflect a network of elaborate regulatory processes interacting across
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Overexpression of AR in a transgenic
2024-11-11

Overexpression of AR in a transgenic mouse model leads to a capsular cataract phenotype involving proliferation and formation of a fibrotic plaque of cells reminiscent of cells at the posterior 33187 australia in PCO [17]. To investigate the molecular mechanism that could link AR expression to this
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Liaohe River situates in the southwestern part
2024-11-11

Liaohe River situates in the southwestern part of Northeast China and flows through Liaoning Province. Due to the rapid urbanization and industrialization, Liaohe River has become one of the most polluted rivers in China. Multitudinous organic pollutants that can induce toxicity to organisms such as
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With one exception all receptors for dopamine DA
2024-11-11

With one exception, all receptors for dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT), and norepinephrine are metabotropic receptors. The five metabotropic DA receptors (D1–D5) in the CNS are involved in motivation, pleasure, cognition, learning, memory, fine motor control, and modulate neuroen
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In order to get a better understanding of this synergy
2024-11-09

In order to get a better understanding of this synergy, we tested the effect of preliminary incubation of cl pdx with non-stimulating concentrations of gonadotropins or FSK before subsequent stimulation by FSK or gonadotropins alone, also at sub-stimulating concentrations. We observed that human LH
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hedgehog signaling Our results showed that oral administrati
2024-11-09

Our results showed that oral administration of cordycepin, in the concentrations of 5 and 10mg/kg for 3weeks, exerted no influence on body weight and hippocampus weight in mice. Although some reports have pointed out that cordycepin had toxic effects because it may be potential for inducing cell dea
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Structure activity relationships biochemical metabolic and m
2024-11-09

Structure–activity relationships [23], [24], [25], [26], biochemical [24], [25], [26], [27], [28], [29], [30], [31], metabolic [19], [27], [28], [29], [30], [31], and molecular [32] investigations have demonstrated that the substrate specificity, as well as other characteristics of T. gondii adenosi
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br Acknowledgement This work was supported by grants from th
2024-11-09

Acknowledgement This work was supported by grants from the American Heart Association Scientist Development Grant (SDG) to A. Elmarakby and 1R01EY023315-01 award to M. Al-Shabrawey. Introduction Inflammatory response is the result of a complex interaction between immune gip receptor and seve
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br Introduction Cell motility is
2024-11-09

Introduction Cell motility is fundamentally important in morphogenesis, wound healing, and the immune response. One of the best-studied basic types of cell movement is lamellipodial motility [1, 2], characterized by a thin (∼0.1–0.2 μm), broad (∼10–40 μm) motile appendage containing a dynamic RGF
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increase protein stability The effect of capital deductions
2024-11-09

The effect of capital deductions on equilibrium prices is given by the following comparative statics Thus, equilibrium prices are strictly decreasing in the share of capital cost deduction. The reason is that a higher share of capital cost deduction reduces the effective marginal costs, which makes
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br Materials and methods br Results
2024-11-09

Materials and methods Results Discussion The brain is endowed with the 5-LOX enzymatic system (Lammers et al., 1996, Lindgren et al., 1984), but its physiological and pathological roles are still not clear. Inflammation is a characteristic of many neurodegenerative diseases such as Alzheime
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In an AP scenario several inflammatory
2024-11-09

In an AP scenario, several inflammatory mediators are produced locally to orchestrate an immune response. Eicosanoids are among those molecules and represent a class of lipid mediators synthesized from arachidonic Ranolazine through the action of cyclooxygenases or lipoxygenases to generate prostag
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Prostate cancer is the second leading cause
2024-11-09

Prostate cancer is the second leading cause of cancer-related death in men in the United States [25]. Similar to pancreatic cancer, prostate cancer has few diagnostic options available, particularly to differentiate indolent from aggressive disease. Axl is also overexpressed in ∼50% of prostate canc
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br Conflict of interest br Acknowledgements We thank
2024-11-09

Conflict of interest Acknowledgements We thank Ann Jackman, Mike Ormerod and members of Julian Downward's and Alan Ashworth's groups for helpful discussions. This work was supported by grant number PEM/GME/D391/40 from the Kidani Trust (S. Kaye) and by Keele University. Introduction Autota
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